Friends don't let friends quilt drunk*!!
If it happens anyway, you may find yourself getting intimately acquainted with your seam ripper.
*In my defense it was only two glasses of red wine. But I drink so infrequently, that those two glasses had me completely looped. Clearly (doh) I thought this was a good time to quilt and add a binding. The next morning, I realized the error of my ways and started unpicking.